Erythropoietic protoporphyria. IV. Protection from sunlight.
نویسندگان
چکیده
Dihydroxyacetone and lawsone, in a vanishing cream base, applied to the skin was found to protect patients with erythropoietic protoporphyria against sunlight. The use of the same ingredients in a 50% isopropyl alcohol/water solution did not induce adequate light protection. The chemically induced ultraviolet light filter in the stratum corneum allowed these patients to change their lives from an "indoor" to an "outdoor" environment.
منابع مشابه
Prevention of photosensitivity with action spectrum adjusted protection for erythropoietic protoporphyria
Erythropoietic protoporphyria is a genetic disease characterized by sensitivity to sunlight caused by the accumulation of protoporphyrin IX. Photoprotection against ultraviolet A and visible light is necessary for erythropoietic porphyria patients because the absorption spectrum of protoporphyrin IX lies in both ultraviolet A and visible light region. We developed a novel index, in vitro porphy...
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A 39-year old Malay male presented with a history of photosensitivity following exposure to sunlight. The skin became itchy for about 20 minutes and was followed by blister formation. The affected skin subsequently showed signs of peeling off. He has had similar experience since the age of 12 years and has learned to avoid unnecessary exposure to sunlight since then. Examination showed areas of...
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متن کاملAdvances in the management of erythropoietic protoporphyria – role of afamelanotide
Erythropoietic protoporphyria (EPP) and the phenotypically similar disease X-linked protoporphyria (XLPP) are inherited cutaneous porphyrias characterized clinically by acute non-blistering photosensitivity, intolerance to sunlight, and significantly reduced quality of life. They are due to marked overproduction of protoporphyrin (PP) chiefly by erythroblasts and reticulocytes. In EPP, the unde...
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ورودعنوان ژورنال:
- British medical journal
دوره 1 5698 شماره
صفحات -
تاریخ انتشار 1970